Gastric ulcer perforation credited to paracoccidioidomycosis. Case report with autopsy

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Mariana Bellaguarda de Castro Sepulvida
Rafael Fantelli Stelini
Pompeu Tomé Ribeiro de Campos
Carlos Osvaldo Teixeira
Maria Aparecida Barone Teixeira

Resumo

Paracoccidioidomycosis or South American blastomycosis is an endemic disease that occurs predominantly in rural South America, caused by a thermo-dimorphic fungus named Paracoccidioides brasiliensis. Its epidemiologic importance relates to its characteristics of transmissibility, susceptibility and morbidity, in addition to its high cost due to prolonged medical monitoring. It has a polymorfism in the description, explained by absent or nonspecific initial symptoms such as night sweats, weight loss or fever, and later symptoms according to its location of involvement. The objective of this study was to report a case of uncommon presentation of this pathology. The case report is the autopsy of a 74-year-old, white, female patient with predominant manifestation in the gastrointestinal tract originating from paracoccidioidomycosis, and complicated by one of the gastric ulcers perforation. This is an unusual presentation, and reports of gastric ulcer perforation credited to this agent were not found in the literature.

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